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What causes high protein creatinine ratio


A urine protein creatinine ratio (UPCR) test is a urine test. It measures the levels of protein and creatinine in your urine (pee). Creatinine is a waste product produced by your muscle cells as they use creatine (a natural chemical that gives your muscles energy). When your kidneys work like they should, they filter waste products, including.

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High blood protein is not a specific disease or condition in itself. It's usually a laboratory finding uncovered during the evaluation of a particular condition or symptom. For instance, although high blood protein is found in people who are dehydrated, the real problem is that the blood plasma is actually more concentrated. Augusta Thorn. A ratio of albumin (mcg/L) to creatinine (mg/L) of less than 30 is regarded normal; a ratio of 30–300 indicates microalbuminuria; while values more than 300 indicate macroalbuminuria. The lowest detection limit of protein on a typical urine dipstick is 10–20 mg/dL. A concentration of albumin greater than 100 mg/dL in urine.

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creatinine (UPC) ratio is a simple test that measures how much protein is being lost through the kidneys. It can be used to determine whether a pet has a serious disease. If the UPC is too high, the pet’s kidneys may not be able to remove enough protein.

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Most common symptoms of Abnormal bun creatinine ratio : Urinary tract obstruction (blockage from being able to pee) Some people may also experience sleeplessness due to the stress. Not getting enough sleep is linked to Heart attack, Depression, High Blood Pressure, Obesity and Diabetes. If you think you are having a sleep disorder, you can take.

High Protein Diet & Creatinine. A medical gloved hand holding a blood sample over a lab report showing hight creatinine levels. A high level of creatinine in the bloodstream is often an indication of kidney dysfunction. A high protein diet, however, can bring about high creatinine levels as well. In spite of its potential toxicity, creatinine.

A urine protein creatinine ratio (UPCR) test is a urine test. It measures the levels of protein and creatinine in your urine (pee). Creatinine is a waste product produced by your muscle cells as they use creatine (a natural chemical that gives your muscles energy). When your kidneys work like they should, they filter waste products, including.

Proteinuria is a common finding in adults in primary care practice. An algorithmic approach can be used to differentiate benign causes of proteinuria from rarer, more serious disorders. Benign.

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We have performed a prospective study with the aim to update the normal upper values of the urinary total protein-to- creatinine and albumin-to- creatinine ratios in term newborns. Methods: Urine samples were collected from 277 healthy, full-term newborns within the first 48 hours (D0-1) and between 72 and 120 h of life (D3-4).

is more of one type of light chain than the other, the ratio will be different, which can be a sign of myeloma. Beta-2 microglobulin This is another protein made by the myeloma cells. Although this protein itself doesn't cause problems, it can be a useful indicator of a patient's prognosis (outlook). High.

A high BUN value may be caused by a high-protein diet, Addison's disease, or tissue damage (such as from severe burns), or from bleeding in the gastrointestinal tract. High BUN -to- creatinine ratios occur with sudden (acute) kidney problems, which may.

Proteinuria is an important indicator of kidney disease and its risk of progression. Albumin:creatinine ratio (ACR) is the preferred test for detection of small amounts of albumin in the urine. Proteinuria and microalbuminuria are both signs of renal involvement in the disease process and are risk factors for cardiovascular morbidity and mortality.

All of which means that if this result shows up in a blood test, further diagnostic procedures or questions and elimination are needed to narrow down the cause. One common misconception is that high bun creatinine ratio can result from a high-protein diet or digestion of proteins. This idea arises because blood, which is high in protein in the.

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Normal Urea - 2.5-10.7mmol/L. Normal Creatinine - 62-106umol/L -> 0.062 - 0.106mmol/L (divide micromoles by 1000) The relationship of urea and creatine is dependent on serum laboratory units used to determine the cause of acute kidney injury. In the US the urea is expressed as BUN (Blood Urea Nitrogen) in mg/dL.

High values for both BUN and creatinine indicate that the kidneys are not working well and may be in failure. In this situation a urine protein:creatinine (UPC) ratio greater than 0.4 in a cat and 0.5 in a dog indicates there is significant protein loss through the kidneys, and a diagnosis of primary kidney disease can be made.

Posts: 185. Very high protein/Creatinine Ratio -- What does this mean? I had a blood and urine test for life ins. All the tests came back normal, except the protein/Creatinine ratio. It's supposed to be between 0 and 200, mine was 470. What could this mean? My creatinine level itself wasn't raised, neither was my BUN count.

Dietary Protein. In people with CKD, eating a high protein diet can contribute to elevation of BUN and creatinine. This is because these lab markers are involved with protein intake and protein stores in the body. The damaged kidneys are unable to remove excess amounts from the blood. The Protein-Creatinine Ratio (PCR) is used to measure the results of a lab test of proteinuria related to chronic kidney disease (CKD). PCR is defined as the ratio of urine protein to Urine Creatinine. Urine protein was measured using either Urine Protein or, when Urine Protein test results were not available, Dipstick Protein Urinalysis.

If the level of creatinine in the blood increases as the disease progresses, it can lead to failure of the kidneys. Kidney Disease Kidney disease is the most common cause of death in people with diabetes. It can be caused by a number of different conditions, including kidney stones, kidney infections, and kidney tumors.

As such, a protein-to-creatinine ratio of 1 g protein/g creatinine in an average-sized person approximates 1 g of proteinuria in 24 hours. It is important to recognize that a ratio of 2.5 g protein/g creatinine in a muscular person who excretes 2 g of creatinine in 24 hours may actually represent nephrotic-range proteinuria of 5 g/day.

Not getting enough sun (or dietary vitamin D) is another possible cause of high CRP. Your diet can have a strong influence on your CRP levels. Diets high in saturated and trans fats and low in vitamins A and K increase CRP levels and inflammation. Hormonal imbalances can also cause high CRP.

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Proteinuria is a broad term used to describe protein in the urine. It is a general term for the presence of proteins, including albumin, globulin, Bence-Jones protein, and mucoprotein in the urine.[1] Almost half of the protein lost in the normal urine is derived from the distal tubule, known as Tamm-Horsfall glycoprotein (THG).[2][3] Persistent proteinuria is a marker of kidney.

Remember, the body uses creatine in muscle metabolism, and that creatine becomes a waste product of that process. Protein fuels that process, which means that too much of it will create extra creatinine and other wastes. If your kidneys aren't working well to filter toxins and waste, you don't want to add to their burden.

is more of one type of light chain than the other, the ratio will be different, which can be a sign of myeloma. Beta-2 microglobulin This is another protein made by the myeloma cells. Although this protein itself doesn't cause problems, it can be a useful indicator of a patient's prognosis (outlook). High.

What can cause high albumin creatinine ratio? Several factors can cause higher than expected urinary microalbumin results, such as: Blood in your urine (hematuria) Certain medications. Fever. Recent vigorous exercise. Urinary tract infection. Other kidney diseases. How do you lower albumin creatinine ratio? How can albuminuria be reduced?.

As kidney damage progresses, or if protein loss is severe, you may develop symptoms such as fluid build-up (edema), shortness of breath, nausea, and fatigue. The production of too much protein, as seen with multiple myeloma, lymphoma, and amyloidosis, can also lead to proteinuria.

The Protein-Creatinine Ratio (PCR) is used to measure the results of a lab test of proteinuria related to chronic kidney disease (CKD). ... A dipstick protein level greater than or equal to 0.3 g/L is considered abnormally high. A comparison of same-day Dipstick and Urine Protein test results showed moderate agreement (kappa = 0.48):.

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The non-SI ratio (BCR) is BUN (mg/dL) / plasma creatinine (mg/dL). The reference range is around 8-15 [5] and the most commonly used cut-off value to define increased BCR is 20. The SI ratio (UCR) is plasma urea (mmol/L) / (plasma creatinine (μmol/L) divided by 1000). The factor of 1000 is needed to convert creatinine result from μmol/L to.

There are a variety of causes of damage, in particular high blood pressure and high blood sugar (diabetes). 3; Cohort: A group of individuals having a statistical factor (as age or class membership) in common in a demographic study. 2; ... Urine protein to creatinine ratio.

Not getting enough sun (or dietary vitamin D) is another possible cause of high CRP. Your diet can have a strong influence on your CRP levels. Diets high in saturated and trans fats and low in vitamins A and K increase CRP levels and inflammation. Hormonal imbalances can also cause high CRP.

Dietary Protein. In people with CKD, eating a high protein diet can contribute to elevation of BUN and creatinine. This is because these lab markers are involved with protein intake and protein stores in the body. The damaged kidneys are unable to remove excess amounts from the blood.

What causes high BUN creatinine ratio in children? A high BUN value may be caused by a high-protein diet, Addison’s disease, or tissue damage (such as from severe burns), or from bleeding in the gastrointestinal tract. High BUN-to-creatinine ratios occur with sudden (acute) kidney problems, which may be caused by shock or severe dehydration.

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generally causes BUN levels to rise more than creatinine levels. This causes a high BUN-to-creatinine ratio. Kidney disease or blockage of the flow of urine from your kidney causes both BUN and creatinine levels to go up. How To Prepare Do not eat meat or other protein before having a blood urea nitrogen (BUN) test. How It Is Done.

Laboratory evaluation of kidney disease. April 30, 2011. The serum chemistry profile, complete blood count, and urinalysis findings that indicate kidney disease. Kidney disease is defined as the presence of functional or structural abnormalities in one or both kidneys ( Figure 1 ). It is recognized by either reduced kidney function or kidney. The following are possible causes of elevated serum creatinine that do not indicate kidney disease: Diet and in particular red meat consumption. Creatine supplements intake. High muscle mass. Exercising. Dehydration. Among the disorders and diseases that may cause the creatinine levels to rise there are:.

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What drugs cause elevated levels of creatinine ? Several drugs , such as cimetidine, trimethoprim, corticosteroids, pyrimethamine, phenacemide, salicylates and active vitamin D metabolites, have been reported to increase plasma creatinine without influencing its glomerular filtration. Laboratory evaluation of kidney disease. April 30, 2011. The serum chemistry profile, complete blood count, and urinalysis findings that indicate kidney disease. Kidney disease is defined as the presence of functional or structural abnormalities in one or both kidneys ( Figure 1 ). It is recognized by either reduced kidney function or kidney.

Common causes of protein in the urine include diabetes, hypertension and glomerulonephritis to name only a few conditions. This test indicates that you have an abnormal amount of protein in your urine possibly caused by damage to the kidney from hypertension (or some other condition if you have one).

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Creatinine is a substance that comes from the catabolism of creatine phosphate. It is this creatine that muscles use. Being active in physical activities, such as weightlifting contributes to a significant increase. If you take a blood test a day after playing sport, it is almost certain that the value will be raised. .

How do I lower my BUN creatinine ratio? Lower creatinine levels by avoiding creatine in your diet and eat more fiber and less protein. You can also limit intense exercise and try supplements like chitosan. High creatinine levels may be a sign of kidney disease, so see a doctor for a diagnosis. Visit Insider’s Health Reference library for more.

urine protein:creatinine ratios >45 mg/mmol (2) The loss of up to 150 mg of protein per day is normal; this may be expressed as normal is less than 4 mg per hour per square metre of body surface area. Proteinuria may be increased by a factor of 2-3 times by strenuous exercise or fever.

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urine protein:creatinine ratios >45 mg/mmol (2) The loss of up to 150 mg of protein per day is normal; this may be expressed as normal is less than 4 mg per hour per square metre of body surface area. Proteinuria may be increased by a factor of 2-3 times by strenuous exercise or fever.

If the level of creatinine in the blood increases as the disease progresses, it can lead to failure of the kidneys. Kidney Disease Kidney disease is the most common cause of death in people with diabetes. It can be caused by a number of different conditions, including kidney stones, kidney infections, and kidney tumors. Sometimes your BUN Creatinine Ratio might be high and you don’t have renal failure at all. You may be eating a high protein diet recently, which would cause your BUN to go higher than your creatinine due to the short term protein metabolism. You also may have a Gastrointestinal Bleed, or be on steroid drug therapy. This is especially true if your Creatinine is normal and your.

The albumin creatinine ratio (ACR) is a ratio that is used to determine how well the kidneys are working. This is a crucial ratio for determining whether or not the kidneys are pathological. However, we should first try to comprehend what albumin and creatinine are. Albumin is a type of protein found in the human body.

But cinnamon does regulate the body's creatinine levels ( 11 ). Mix ½ a tablespoon of cinnamon in warm water or food and consume once a day. 4. Chamomile Tea. Ingestion of chamomile tea may lower high creatinine levels ( 12 ). Add chamomile herb to a cup of hot water. Allow it to steep for at least 10 minutes.

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Most common symptoms of Abnormal bun creatinine ratio : Urinary tract obstruction (blockage from being able to pee) Some people may also experience sleeplessness due to the stress. Not getting enough sleep is linked to Heart attack, Depression, High Blood Pressure, Obesity and Diabetes. If you think you are having a sleep disorder, you can take.

Emotional stress. Fever. Heat exposure. Difficult workout. Diseases and conditions that can cause constantly elevated levels of protein in urine, which may show kidney disease, include: Amyloidosis (accumulation of irregular proteins in your organs). Particular drugs. Chronic kidney disease. Diabetes.

There are only two variables needed to estimate the rate of urinary protein excretion. You don't need to know the urine volume or output for the calculation of UPCR, just the. Urine protein (expressed in mg/dL); and; Urine creatinine ( expressed in mg/dL).; The following formula the protein creatinine ratio calculation:. Urinary protein excretion (g/day) = Urine protein / Urine.

Chemicals That Affect Urine Color . Human urine ranges in color from nearly clear to dark amber, depending largely on the amount of water that is present. A variety of drugs, natural chemicals from foods, and diseases can alter the color. For example, eating.

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The urine protein to creatinine ratio on random mid-day urine samples correlates well to 24-hour urine collection, for quantitating urinary protein loss. The degree of proteinuria yields useful information on the source of protein loss; namely losses of large amounts of protein (with high urine protein to creatinine ratios) is due to glomerular.

Drugs cause approximately 20 percent of community-and hospital-acquired episodes of acute renal failure. 1 – 3 Among older adults, the incidence of drug-induced nephrotoxicity may be as high as .... "/> lemon mints strain review. ftid method 2021.. The urinary protein-to-creatinine ratio (UPCR) normalizes protein excretion to the glomerular filtration rate and therefore remains unaffected by hydration status . While the gold standard method for quantifying proteinuria is 24-hour urine protein , this important procedure has a certain time limit for detection. Furthermore, it is.

Chemicals That Affect Urine Color . Human urine ranges in color from nearly clear to dark amber, depending largely on the amount of water that is present. A variety of drugs, natural chemicals from foods, and diseases can alter the color. For example, eating. If the protein-to-creatinine ratio comes back high, then she turns to the gold standard: a 24-hour urine collection test. ... More serious complications include HELLP syndrome, which can cause you.

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A BUN/Creatinine ratio above the normal range can be caused by: Dehydration. Dehydration increases the blood levels of both BUN and creatinine but increases BUN more than creatinine [ 11 ]. Gut bleeding. The blood in the gut gets digested and this increases the amount of protein and BUN levels [ 12, 13 ]. Hyperthyroidism.

High BUN -to- creatinine ratios occur with sudden (acute) kidney problems, which may be caused by shock or severe dehydration.A very high BUN -to- creatinine ratio may be caused by bleeding in the digestive tract or respiratory tract.Low values.A low BUN value may be caused by a diet very low in protein, by malnutrition, or by severe liver damage.

It’s difficult to diagnose multiple myeloma early. Often, multiple myeloma causes no symptoms until it reaches an advanced stage. Sometimes, it might cause vague symptoms that at first seem to be caused by other diseases. Sometimes, multiple myeloma is found early when a routine blood test shows an abnormally high amount of protein in the blood. The most common cause of proteinuria is diabetes, and in any person with proteinuria and diabetes, the cause of the underlying proteinuria should be separated into two categories: diabetic proteinuria versus the field. With severe proteinuria, general hypoproteinemia can develop which results in diminished oncotic pressure.

Creatinine is a substance that comes from the catabolism of creatine phosphate. It is this creatine that muscles use. Being active in physical activities, such as weightlifting contributes to a significant increase. If you take a blood test a day after playing sport, it is almost certain that the value will be raised. It is possible, however, to lose significant amounts of other proteins of lower molecular size (e.g. in renal tubular disease or in light chain disease) without necessarily seeing an increase in albumin loss. Some drugs may cause an analytical interference in assessing protein levels. Further information Lab Tests Online Albumin:Creatinine Ratio.

In medicine, the BUN-to-creatinine ratio is the ratio of two serum laboratory values, the blood urea nitrogen (BUN) ... It is increased by a high-protein diet, by gastrointestinal bleeding (based on plasma protein level of 7.5 g/dl and a hemoglobin of 15 g/dl, 500 ml of whole blood is equivalent to 100 g protein), by catabolic processes such as. Since urea is non toxic, it is eliminated via urine. Now, generally speaking, a high protein diet will also cause muscle gain, and hence the blood creatinine level will eventually rise and catch up, normalizing the BUN: creatinine ratio. Thus, high protein intake can cause a high BUN/Creatinine ratio but only initially. See below: An elevated BUN with normal creatinine and a ratio of [generally more than 18-20] occurs most commonly in dehydrated individuals and is not a sign of... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. 5.8k views Reviewed >2 years ago. Thank.

There are many possible causes of high creatinine, some of which may be a one-time occurrence. Examples can include things such as dehydration or intake.

Augusta Thorn. A ratio of albumin (mcg/L) to creatinine (mg/L) of less than 30 is regarded normal; a ratio of 30–300 indicates microalbuminuria; while values more than 300 indicate macroalbuminuria. The lowest detection limit of protein on a typical urine dipstick is 10–20 mg/dL. A concentration of albumin greater than 100 mg/dL in urine. Proteinuria may be increased by a factor of 2-3 times by strenuous exercise or fever. other causes of transient include urinary tract infection, vaginal mucus, orthostatic proteinuria (occurs after patient has been upright for some time and is not found in early morning urine - this condition is uncommon in patients over 30 years old) and pregnancy.

The urinary albumin:creatinine ratio is a useful measure of renal function used in diabetic renal disease. The urinary albumin:creatinine ratio is measured using the first morning urine sample where practicable. Microalbuminuria is defined as: albumin:creatinine ratio >2.5mg/mmol (men) or >3.5mg/mmol (women) or albumin concentration >20mg/l. Albumin/creatinine ratio. Another interpretation of urine creatinine count is called the albumin/creatinine ratio. Albumin is a protein in blood. Healthy kidneys generally don't filter it out of the blood, so there should be little to no albumin found in the urine.

The non-SI ratio (BCR) is BUN (mg/dL) / plasma creatinine (mg/dL). The reference range is around 8-15 [5] and the most commonly used cut-off value to define increased BCR is 20. The SI ratio (UCR) is plasma urea (mmol/L) / (plasma creatinine (μmol/L) divided by 1000). The factor of 1000 is needed to convert creatinine result from μmol/L to. The urinary protein-to-creatinine ratio (UPCR) normalizes protein excretion to the glomerular filtration rate and therefore remains unaffected by hydration status . While the gold standard method for quantifying proteinuria is 24-hour urine protein , this important procedure has a certain time limit for detection. Furthermore, it is. The name of the urine test that measures the level of albumin in your urine is called the urine albumin-to-creatinine ratio (UACR). A UACR compares the level of albumin to the level of creatinine (a waste product in your blood that comes from your muscles). A normal UACR is less than 30mg/g. If your UACR is 30 mg/g or higher, it can be a sign.

We have performed a prospective study with the aim to update the normal upper values of the urinary total protein-to- creatinine and albumin-to- creatinine ratios in term newborns. Methods: Urine samples were collected from 277 healthy, full-term newborns within the first 48 hours (D0-1) and between 72 and 120 h of life (D3-4).

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Augusta Thorn. A ratio of albumin (mcg/L) to creatinine (mg/L) of less than 30 is regarded normal; a ratio of 30–300 indicates microalbuminuria; while values more than 300 indicate macroalbuminuria. The lowest detection limit of protein on a typical urine dipstick is 10–20 mg/dL. A concentration of albumin greater than 100 mg/dL in urine.

Get your kidneys checked at least every year. Your healthcare team will do a simple blood test to find out your eGFR. They will also do a urine albumin-creatinine ratio (uACR), which shows if you have protein (albumin) in the urine. Protein in the urine may mean you have kidney damage. Control blood pressure if you have high blood pressure.

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Sometimes your BUN Creatinine Ratio might be high and you don’t have renal failure at all. You may be eating a high protein diet recently, which would cause your BUN to go higher than your creatinine due to the short term protein metabolism. You also may have a Gastrointestinal Bleed, or be on steroid drug therapy. This is especially true if your Creatinine is normal and your. There are many possible causes of high creatinine, some of which may be a one-time occurrence. Examples can include things such as dehydration or intake. Proteinuria is protein, usually albumin, in urine. High concentrations of protein cause frothy or sudsy urine. ... which can be measured in a 24-hour urine collection or estimated by random urine protein/creatinine ratio (values > 0.3 are abnormal); for albumin it is about 30 mg/day. Albumin excretion between 30 and 300 mg/day (20 to 200 mcg. Heart disease. Heart failure. Hodgkin's lymphoma (Hodgkin's disease) Kidney infection (pyelonephritis) Malaria. Orthostatic proteinuria (urine protein level rises when in an upright position) Rheumatoid arthritis. Causes shown here are commonly associated with this symptom. In this situation a protein:creatinine (UPC) ratio up to 2.0 in both cats and dogs is acceptable. ... 🐶 What causes high creatinine in dogs? High muscle production of creatinine, especially in dog breeds with large muscle mass, such as boxers, greyhounds, sled dogs, etc. Reduction in extracellular fluid volume:. Hypothyroidism is a condition in which thyroid glands produce fewer hormones than needed by the body, which leads to multiple physical concerns. In hypothyroidism renal blood flow and Glomerular filtration rate (GFR) resulting in low creatinine and urea. In mild cases of hypothyroidism, there are no noticeable effects on creatinine levels. High Protein Diet & Creatinine. A medical gloved hand holding a blood sample over a lab report showing hight creatinine levels. A high level of creatinine in the bloodstream is often an indication of kidney dysfunction. A high protein diet, however, can bring about high creatinine levels as well. In spite of its potential toxicity, creatinine.

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The albumin creatinine ratio (ACR) is a ratio that is used to determine how well the kidneys are working. This is a crucial ratio for determining whether or not the kidneys are pathological. However, we should first try to comprehend what albumin and creatinine are. Albumin is a type of protein found in the human body. Most cases of protein in urine during pregnancy can’t be prevented. Conditions such as preeclampsia are often inherited disorders. Underlying conditions that may cause protein in urine to increase, such as diabetes, lupus, and hypertension, may also be genetic or have complex medical and autoimmune causes. 1.

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Sometimes a positive dipstick for protein isn’t abnormal, for example concentrated samples first thing in the morning, or if you have become dehydrated or haven’t drunk much. Lab tests can sort this out (protein/creatinine ratio or albumin/creatinine ratio) Temporary proteinuria may occur after vigorous exercise or if you have a high fever. A high BUN value may be caused by a high-protein diet, Addison's disease, or tissue damage (such as from severe burns), or from bleeding in the gastrointestinal tract. High BUN -to- creatinine ratios occur with sudden (acute) kidney problems, which may.